CURRICULUM VITAE

Univ. - Prof. Dr. med. Carsten Tschöpe
Professor of Medicine and Cardiology
Vice Director of the Dept. of Cardiology, Charité, CVK

Charité - Universitaetsmedizin Berlin
Campus Virchow
Department of Cardiology
Augustenburger Platz 1
D-13353 Berlin



                        
 

Research Networks

Ãœbergabe Arthur Weber Preis

Research colleagues, co-workers



Academic backround

1986-1993     Human medicine studies in Heidelberg
1993     State examination and doctorate in medicine
Postdoctoral recipient of a grant from the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) graduate college "Kidney and circulation research" at the university of Heidelberg
Occupation as medical doctor in training and scientific research colleague in the field of inner medicine at the university of Heidelberg focussing on nephrology
1995     Occupation as assistant medical doctor and scientific research colleague in pharmacology at the university of Kiel
since 1996     Occupation in the field of internal medicine in the Medical Clinic II of Charité - University Medicine Berlin, Campus Benjamin Franklin concentrating on cardiology and pulmonology
2002     Specialist for internal medicine
2003     Habilitation in the Department of Cardiology at the Charité University Hospital in Berlin
since 2004     Intermediary assistant medical director in the clinic
2006-2010     assistant medical director of the intensive station
       
since 2007     assistant medical director of the clinic and deputy consultant of the department of cardiology and pulmonology at Charité, Campus Benjamin Franklin (CBF) in Berlin
since 2009



since 2015
    additional W2 - university professorship in the Translation Centre "Berllin Brandenburg Centre for regenerative therapies" (Berlin Brandenburger Zentrum für regenerative Therapien, BCRT) for the development of cell thereapeutic options regarding heart failure

Vice Director of the Dept. of Cardiology, at the Campus Virchow Clinic (CVK) at the Charite, Berlin
Guiding the Cardiomyopathy program

Additional qualifications

  • Specialist for Internal Medicine
  • Specialist for cardiology
  • Specialist for intensive-care medicine
  • Specialist for interventional cardiology incl. TAVI and Mitral-Clip program

Main research areas promoted by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) and the Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung, BMBF)

  • Scholarship recipient (Graduiertenkolleg, GRK) as post-doctorate in "Kidney and circulation research" in regard to diabetic nephropathy 1993-1995 (University of Heidelberg)
  • DFG: individual application for diabetic cardiopathy (TC-64-1) 1997-1999 (Charité, Berlin)
  • DFG: extention of that application for diabetic cardiopathy (TC-64-2) 1999-2001 (Charité, Berlin)
  • GRK 865: project manager of Diabetes mellitus induced endothelial dysfunktion 2003-2007 (Charité, Berlin)
  • Trans-regional special research areas (Transregio-Sonderforschungsbereich, (TR SFB19): project manager B5 of diastolic dysfunktion 2004-2010, Charité, Berlin)
  • TR SFB19: product manager Z3 of Care Facility: haemodynamic characterization 2004-2010 (Charité, Berlin)
  • BMBF: platform manager of BCRT for cardial regenerative medicine (total promotional volume: 12 million Euros over 12 years; platform promotion: 100,000 Euros each year


Inflammatory Cardiomyopathy and Biopsies

Heart Failure with Preserved EF (HFpEF)

Cell-Therapy and Immunocardiology

Berlin-Brandenburg Center for Regenerative Therapies (BCRT)

Honours, Awards, Fellowships, Memberships of Professional Societies Awards

1997 MSD-Herzinsuffizienzpreis
1998 Irbesartan Award
2000 Research Prize of the Benjamin Franklin University Clinic (2nd Prize)
2001 Research Prize of the Benjamin Franklin University Clinic (2nd Prize)
2003 Research Prize of the Benjamin Franklin University Clinic (1st Prize)

Memberships:
  • German Cardiac Society
  • German Society for Internal Medicine
  • Excellence Cluster of the Charité: “Junge Charité"
  • European Society of Cardiology
  • European Society of Diabetes mellitus
  • Vice Group leader of the European Study Group on “Diastolic Heart Failure” (ESC)
  • Member of the Working Group "Myocardial and Pericardial Diseases" (ESC)

Patents

  • Cell Therapy: "CAPS for Cardial Regeneration"
  • Diagnostics: "PVB for Bone Marrow and Cell Transplantation"
  • Therapie : "B-Cell Therapy for Heart Failure"

Prices

1998    MSD–Herzinsuffizienzpreis
1999    BMS-Forschungspreis
2000    UKBF-Forschungspreis
2001    UKBF-Forschungspreis
2004    Herzinsuffizienz-Posterpreis der DKG
2006    Forschungspreis der Europäischen Diabetes Gesellschaft
2007    Charite Habilitationsstipendium
2008    BCRT-Kick off Grand
2009    CMV-Novartis Preis
2012    Arthur-Weber Preis der DGK für die Entwicklung neuer Therapieoptionen bei der Herzinsuffizienz und der Kardiomyopathie.

                                                                      Ãœbergabe Arthur Weber Preis




  

Principle or CO-Investigator of clinical studies

- For hypertension treatment REAL-Study
- For mitral valve insufficiency Evolution-I-Study, Evolution-II-Study
- For diastolic heart failure I-Preserve, DDD-Studie, Fibro-Aldo
- For acute heart failure Veritas-2-Study
- For stem cell therapy of heart attacks Boost-2-Study
- For chronic heart failure Escape-Study
- For stem cell therapy of DCMi Steb-1 (underway)
- For stem cell therapy of CLI PLX-PAD-Study

Academic Publications

250 publications (incl. overview- and bookarticles, 170 international original articles)

PUB MED

Scientific work
            Publications/Year                                                 Citations / Year


Impact factors: 1560
HI. Index: 50
Publications : 250 (12/2016)

Most important publications (from 250)

Miteva K, Pappritz K, El-Shafeey M, Dong F, Ringe J, Tschöpe C, Van Linthout S. Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3-Induced Myocarditis.
Stem Cells Transl Med. 2017 Jan 3.

1. Miteva K, Pappritz K, El-Shafeey M, Dong F, Ringe J, Tschöpe C, Van Linthout S. Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3-Induced Myocarditis. Stem Cells Transl Med. 2017 Jan 3.

2. Yang J, Savvatis K, Kang JS, Fan P, Zhong H, Schwartz K, Barry V, Mikels-Vigdal A, Karpinski S, Kornyeyev D, Adamkewicz J, Feng X, Zhou Q, Shang C, Kumar P, Phan D, Kasner M, López B, Diez J, Wright KC, Kovacs RL, Chen PS, Quertermous T, Smith V, Yao L, Tschöpe C, Chang CP. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016 Dec 14;7:13710.
 
3.  Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M, Cammann VL, Sarcon A, Geyer V, Neumann CA, Seifert B, Hellermann J, Schwyzer M, Eisenhardt K, Jenewein J, Franke J, Katus HA, Burgdorf C, Schunkert H, Moeller C, Thiele H, Bauersachs J, Tschöpe C, Schultheiss HP, Laney CA, Rajan L, Michels G, Pfister R, Ukena C, Böhm M, Erbel R, Cuneo A, Kuck KH, Jacobshagen C, Hasenfuss G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Cuculi F, Banning A, Fischer TA, Vasankari T, Airaksinen KE, Fijalkowski M, Rynkiewicz A, Pawlak M, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, Erne P, Bax JJ, Ford I, Ruschitzka F, Prasad A, Lüscher TF. Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. N Engl J Med. 2015 Sep 3;373(10):929-38. 
 
4. Savvatis K, Pappritz K, Becher PM, Lindner D, Zietsch C, Volk HD, Westermann D, Schultheiss HP, Tschöpe C. Interleukin-23 deficiency leads to impaired wound healing and adverse prognosis after myocardial infarction. Circ Heart Fail. 2014 ;7:161-71. 
 
5. Paulus WJ, Tschöpe C. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol. 2013 Jul 23;62(4):263-71.
 
 6. Westermann D, Kasner M, Steendijk P, Spillmann F, Riad A, Weitmann K, Hoffmann W, Poller W, Pauschinger M, Schultheiss HP, Tschöpe C. Role of left ventricular stiffness in heart failure with normal ejection fraction. Circulation. 2008 Apr 22;117(16):2051-60. Epub 2008 Apr 14.
 
7. Kasner M, Westermann D, Steendijk P, Gaub R, Wilkenshoff U, Weitmann K, Hoffmann W, Poller W, Schultheiss HP, Pauschinger M, Tschöpe C. Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative doppler-conductance catheterization study. Circulation. 2007 Aug 7;116(6):637-47
 
8. Tschöpe C, Bock CT, Kasner M, Noutsias M, Westermann D, Schwimmbeck PL, Pauschinger M, Poller WC, Kühl U, Kandolf R, Schultheiss HP.High prevalence of cardiac parvovirus B19 infection in patients with isolated left ventricular diastolic dysfunction. Circulation. 2005 Feb 22;111(7):879-86. 
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